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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
42.42
Human Site:
Y1391
Identified Species:
77.78
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
Y1391
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
Y1391
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
Y1391
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Dog
Lupus familis
XP_851777
2404
260682
Y1356
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
Y1392
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Rat
Rattus norvegicus
NP_596872
2444
265618
Y1392
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
Y1390
E
M
S
E
S
F
P
Y
R
T
K
A
L
F
A
Frog
Xenopus laevis
NP_001088637
2428
264402
Y1382
E
M
P
E
S
F
P
Y
R
T
K
A
L
F
A
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
E1216
S
I
K
E
L
E
Q
E
E
E
E
R
K
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
Y2012
E
M
M
N
E
F
P
Y
R
A
K
A
L
F
A
Honey Bee
Apis mellifera
XP_001122031
2606
284119
Y1591
D
M
P
G
E
F
P
Y
R
A
K
A
L
F
A
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
E1161
C
V
Q
D
K
E
A
E
V
K
A
Q
M
K
Q
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
Y1599
D
L
P
D
T
F
P
Y
R
S
K
A
L
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
6.6
N.A.
73.3
66.6
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
20
N.A.
73.3
73.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
16
8
85
0
0
85
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
0
70
16
16
0
16
8
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
85
0
0
0
0
0
0
0
85
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
0
8
85
0
8
16
0
% K
% Leu:
0
8
0
0
8
0
0
0
0
0
0
0
85
0
0
% L
% Met:
0
77
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
24
0
0
0
85
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
85
0
0
8
0
0
0
% R
% Ser:
8
0
54
0
62
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
62
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _